Analytical instrumentation

Discovery DSC 250 –Differential Scanning Calorimeter

The TA Instruments Discovery DSC 250 is a high‑performance differential scanning calorimeter designed for precise and reliable thermal analysis across research, development, and quality control applications. It combines advanced heat‑flow technology, robust hardware design, and an intuitive user interface to deliver accurate characterization of thermal transitions in polymers, pharmaceuticals, foods, chemicals, and advanced materials.

At the core of the Discovery DSC 250 is the Fusion Cell™, engineered to provide exceptional baseline flatness, sensitivity, and reproducibility. This cell design enables accurate detection of subtle thermal events and highly reliable measurement of transition temperatures, enthalpy changes, and heat capacity. 

The instrument incorporates patented Tzero® heat‑flow technology, which directly measures heat flow rather than relying on mathematical approximations. This approach significantly improves baseline stability and resolution while enabling direct and accurate heat‑capacity determination. Tzero® technology also supports Modulated DSC® (MDSC®) experiments, allowing efficient separation of overlapping thermal events such as reversible and non‑reversible transitions

A wide range of refrigerated cooling options is available, allowing sub‑ambient operation without the need for liquid nitrogen and supporting extended unattended measurements. The Discovery DSC 250 can be configured with a reliable linear autosampler, enabling automated calibration, verification routines, and high‑throughput operation for 24/7 laboratory workflows. 

User interaction is streamlined through a modern touch‑screen interface and integration with TA Instruments’ TRIOS™ software, which provides comprehensive instrument control, method development, data analysis, and reporting in a single environment. Automated calibration tools and flexible experiment design enhance productivity while ensuring data integrity.

The Discovery DSC 250 is suitable for measuring thermal properties such as glass transition temperature, melting and crystallization behavior, phase transitions, enthalpy, heat capacity, cure kinetics, and oxidative stability, making it a versatile platform for both routine analyses and advanced thermal research.

Backed by TA Instruments’ commitment to quality—including an industry‑leading cell and furnace warranty—the Discovery DSC 250 offers long‑term reliability and confidence for demanding laboratory environments.

Uncle – The All-in-One Biologics Stability Screening Platform

Uncle is the first and only 

all-in-one instrument that combines three powerful detection modes—fluorescence, Static Light Scattering (SLS), and Dynamic Light Scattering (DLS)—to deliver comprehensive biologics stability data in a single run. Designed to streamline workflows and conserve precious samples, Uncle enables researchers to screen up to 48 samples simultaneously using just 9 µL per sample, making it ideal for early-stage formulation development, protein engineering, and gene therapy applications.

Key Capabilities

• Thermal Unfolding (Tm) and Aggregation (Tagg): Measure both unfolding and aggregation events concurrently to understand when and how proteins destabilize.
• Isothermal Stability: Assess long-term storage potential by simulating static temperature conditions early in development.
• Capsid Integrity for AAVs: Detect DNA leakage before capsid rupture using SYBR Gold fluorescence, enabling early insight into vector stability.
• Sizing & Polydispersity: Characterize particle size distributions and monitor changes during thermal ramps.
• Viscosity, B22, kD, and G22: Evaluate formulation behavior and aggregation risk at various concentrations, including ultra-high protein levels.

Smart Sample Handling

Uncle uses sealed quartz capillaries (Unis) to prevent evaporation and contamination, allowing for short or extended experiments. Whether you're running a quick DLS scan or a multi-day stability study, Uncle adapts to your workflow.

Full-Spectrum Fluorescence

Uncle captures the entire fluorescence spectrum, eliminating the need to pre-select wavelengths or dyes. This flexibility supports both intrinsic fluorescence and dye-based assays, making it suitable for a wide range of proteins and payloads.

Regulatory Ready

With 21 CFR Part 11 compliant software, Uncle is built for regulated environments, ensuring data integrity and secure access control.

Thermo Scientific™ TSQ Quantum™ Access MAX

The TSQ Quantum Access MAX from Thermo Fisher Scientific is a high-performance triple quadrupole mass spectrometer designed to deliver exceptional sensitivity, specificity, and productivity across a wide range of analytical applications. Whether you're working in pharmaceutical development, environmental testing, food safety, clinical research, or forensic toxicology, this instrument provides robust and reliable results with advanced features tailored for demanding workflows.

Key Features

• Wide Mass Range: Covers 10 to 3000 m/z, enabling comprehensive analyte detection across diverse sample types.
• Quantitation-Enhanced Data-Dependent MS/MS (QED-MS/MS): Simultaneously performs compound quantification and structural confirmation, streamlining multi-residue screening and metabolite identification.
• High-Resolution SRM (H-SRM): Achieves precise quantification with 2 ms dwell times, supporting hundreds of compounds in a single run.
• Fast Polarity Switching: 25 ms switching between positive and negative ion modes enhances throughput and enables simultaneous analysis of multiple compound classes.
• Timed SRMs: Supports up to 3,000 definable timed SRMs, improving sensitivity and reducing cycle times for complex analyses.
• Zero Cross-Talk Collision Cell: Ensures clean transitions and eliminates false positives during high-speed scanning.
• Versatile Ionization Source: The HESI-II (Heated Electrospray Ionization) source offers superior desolvation and accommodates a wide range of flow rates, making it ideal for both low and high-throughput workflows.

Software & Workflow Integration

• Xcalibur™ Data System: Provides intuitive instrument control and method development tools.
• LCQUAN™: A secure, 21 CFR Part 11-compliant platform for regulated quantitative analysis.
• TraceFinder™: Simplifies routine screening and quantitation with preconfigured methods and reports.

Applications

• Pharmaceutical Development: Drug discovery, impurity profiling, and pharmacokinetics.
• Environmental Testing: Detection of pollutants and contaminants in water, soil, and air.
• Food Safety: Multi-residue screening for pesticides, antibiotics, and additives.
• Clinical Research: Biomarker quantification and therapeutic drug monitoring.
• Forensic Toxicology: Identification and quantification of illicit substances and toxic compounds.

Why Choose TSQ Quantum Access MAX?

• Reliable Performance: Proven accuracy and reproducibility in complex matrices.
• Enhanced Productivity: Fast switching and timed SRMs streamline workflows.
• Cost-Effective: Available refurbished to original specifications, offering high value at a lower cost.

Thermo Scientific™ UltiMate™ 3000 LC System

High-Performance Liquid Chromatography for Every Lab

The UltiMate 3000 LC System from Thermo Fisher Scientific is a versatile and modular platform designed to meet the diverse needs of analytical laboratories. Whether you're conducting routine analyses or advanced research, the UltiMate 3000 delivers precision, reliability, and scalability across HPLC and UHPLC workflows.

Key Features

• Modular Design: Available in multiple configurations including Rapid Separation (RS), Standard (SD), Basic, and Semi-Preparative systems.
• UHPLC Compatibility: Supports pressures up to 620 bar (9,000 psi) and flow rates up to 10 mL/min, enabling high-resolution separations.
• Integrated Automation: Combines autosampler and column compartment in one module for space-saving and cost-efficient operation.
• Advanced Pumping Systems: Binary and ternary gradient pumps offer precise flow control and gradient formation for complex separations.
• NanoViper™ Connections: Fingertight fittings ensure leak-free, low-dispersion connections for nano, capillary, and micro flow LC.
• SmartStartup™ Function: Automatically equilibrates the system and initiates sample analysis based on user-defined criteria.

Performance Highlights

• Injection Precision: <0.4% RSD for 1 µL full-loop injections; carryover <0.02% for caffeine.
• Detector Options: UV/Vis detectors with up to 200 Hz data collection rate and wavelength range of 190–900 nm.
• Temperature Control: Column compartment thermostats from ambient +7 °C to 75 °C with ±0.1 °C stability.
• Software Integration: Compatible with Chromeleon™ CDS, Xcalibur™, and other MS platforms for seamless data acquisition and analysis.

Applications

• Pharmaceutical & Biotech: Drug development, impurity profiling, and stability testing.
• Food & Beverage: Residue analysis, quality control, and nutritional profiling.
• Environmental Testing: Detection of pollutants and trace contaminants.
• Academic Research: Ideal for teaching and method development in university labs.

Why Choose UltiMate 3000?

• Reliable and Rugged: Engineered for long-term performance with minimal maintenance.
• Flexible and Scalable: Easily upgradeable with additional modules to meet evolving analytical needs.
• Cost-Effective: Low initial investment and minimal cost of ownership make it ideal for budget-conscious labs.

Thermo Scientific™ LTQ Velos Pro

Linear Ion Trap LCMS

The LTQ Velos Pro from Thermo Fisher Scientific is a next-generation linear ion trap mass spectrometer designed for researchers who demand exceptional speed, sensitivity, and versatility in their workflows. Built on the proven LTQ platform, the Velos Pro introduces advanced ion optics and dual-pressure trap technology to deliver superior performance for complex sample analysis.

Key Features

• Dual-Pressure Linear Ion Trap
• Optimized for both high-resolution MS/MS and ultra-fast scanning, enabling improved sensitivity and dynamic range for low-abundance analytes.
• High-Speed Scanning
• Achieves scan rates up to 52,000 amu/sec, supporting rapid data acquisition for high-throughput experiments.
• Enhanced Ion Transmission
• Advanced ion optics maximize ion capture efficiency, improving signal-to-noise ratio and overall sensitivity.
• Versatile Ionization Options
• Compatible with multiple sources including ESI, APCI, and nanoLC setups for a wide range of applications.
• Dynamic Range & Sensitivity
• Detects low femtomole levels of peptides and small molecules, making it ideal for proteomics and metabolomics studies.

Performance Highlights

• MS/MS Capabilities
• Supports CID (Collision-Induced Dissociation), ETD (Electron Transfer Dissociation), and HCD (Higher-Energy Collisional Dissociation) for comprehensive structural analysis.
• Fast Polarity Switching
• Enables simultaneous analysis of positive and negative ions in complex samples.
• Robust Software Integration
• Fully compatible with Thermo Scientific Xcalibur™ and Proteome Discoverer™ for streamlined data acquisition and interpretation.

Applications

• Proteomics: In-depth peptide sequencing and post-translational modification analysis.
• Metabolomics: Identification and quantification of small molecules in biological samples.
• Drug Discovery: Structural elucidation and impurity profiling.
• Environmental & Food Testing: Trace-level contaminant detection.

Thermo Fisher Headspace GC-MS System

Advanced Volatile Analysis with Modular Precision

The Thermo Fisher Headspace GC-MS system is a powerful, modular solution designed for high-throughput, high-sensitivity analysis of volatile organic compounds (VOCs) across diverse applications—from environmental monitoring to pharmaceutical quality control. This integrated system combines four cutting-edge components:

ISQ™ 7610 Single Quadrupole GC-MS

• High Sensitivity & Robustness: Delivers consistent, reproducible results with extended dynamic range for complex matrices.
• NeverVent™ Technology: Enables column changes and source cleaning without venting the system, minimizing downtime.
• SmartStatus™ Monitoring: Integrated with Chromeleon CDS for real-time instrument health tracking and predictive maintenance.
• Flexible Configurations: Upgradeable from entry-level to advanced setups for evolving analytical needs. [thermofisher.com]

TRACE™ 1300 Gas Chromatograph

• Modular Design: Offers interchangeable injector and detector modules for tailored workflows.
• Fast Ramp Rates: Ensures rapid temperature changes for efficient separations.
• Compact Footprint: Saves valuable bench space while maintaining high performance.

TriPlus™ 500 Headspace Autosampler

• Valve-and-Loop Technology: Ensures precise, repeatable injections with minimal carryover.
• Scalable Throughput: Supports 12 to 240 vials without compromising performance.
• Quick Spin Shaking: Enhances sample equilibration for improved sensitivity.
• Direct Column Connection: Minimizes sample path length for better recovery of polar and high-boiling compounds. [thermofisher.com]

AI 1310 Autosampler

• Automated Liquid Injection: Complements headspace sampling with flexible liquid injection capabilities.
• High Precision: Ensures consistent sample delivery for quantitative analysis.
• Seamless Integration: Works in tandem with TRACE 1300 and ISQ 7610 for unified control and data acquisition.

Key Benefits

• Unmatched Flexibility: Configure for headspace, liquid, or dual-mode sampling.
• Regulatory Ready: Ideal for food safety, environmental, and pharmaceutical testing.
• Optimized Workflow: Automated processes reduce human error and increase throughput.
• Compact & Scalable: Designed for labs with evolving needs and limited space.

Advanced Particle Size Analysis for Precision and Productivity

The Mastersizer 2000 from Malvern Instruments is a high-performance laser diffraction particle size analyzer designed to deliver accurate, reproducible measurements across a wide range of sample types. Ideal for research and quality control environments, it combines cutting-edge optics with intuitive software to simplify particle characterization.

Key Features

• Wide Measurement Range
• Measures particle sizes from 0.02 µm to 2000 µm, covering fine powders, emulsions, suspensions, and granules.
• Laser Diffraction Technology
• Utilizes advanced optical systems for rapid, non-destructive particle size analysis with minimal sample preparation.
• Flexible Dispersion Options
• Compatible with both wet and dry dispersion units, enabling analysis of diverse materials under controlled conditions.
• High Throughput
• Fast measurement cycles (typically under 60 seconds) support routine QC and large sample batches.
• User-Friendly Software
• Malvern’s Mastersizer software provides automated method development, real-time data visualization, and compliance with ISO and USP standards.

Performance Highlights

• Accuracy & Repeatability
• Delivers precise particle size distributions with robust statistical confidence.
• Automated Alignment
• Ensures optimal optical performance for consistent results.
• Data Integrity
• Full audit trails and 21 CFR Part 11 compliance for regulated environments.

Applications

• Pharmaceuticals: Tablet formulation, inhalation products, and controlled-release systems.
• Food & Beverage: Powdered ingredients, emulsions, and flavor encapsulation.
• Chemicals & Minerals: Pigments, fillers, and raw material characterization.
• Cosmetics: Creams, lotions, and powders for texture and stability optimization.

Why Choose Mastersizer 2000?

• Proven Reliability: Trusted by thousands of labs worldwide.
• Versatile Analysis: Handles a broad range of sample types and sizes.
• Regulatory Compliance: Meets international standards for particle size measurement

Particle Size and Zeta Potential Analyzer – Malvern Panalytical Zetasizer®

General Description

The Malvern Panalytical Zetasizer® is a bench‑top light‑scattering analytical instrument for the characterization of particle and molecular systems in liquid dispersion. It is widely used for measuring hydrodynamic particle size, zeta potential (surface charge), molecular weight, and—depending on model—particle concentration.

Zetasizer instruments are based on dynamic light scattering (DLS) and electrophoretic light scattering (ELS), with advanced optical configurations such as Non‑Invasive Back Scatter (NIBS®) and Multi‑Angle Dynamic Light Scattering (MADLS®) to enable accurate, reproducible measurements across a wide particle size and concentration range. 

Key Applications

• Particle and nanoparticle size determination
• Zeta potential and colloidal stability analysis
• Protein and polymer characterization
• Molecular weight determination in solution
• Formulation development and stability studies
• Quality control and research measurements in liquids 

Measured Parameters

• Particle size (hydrodynamic diameter)
• Zeta potential / electrophoretic mobility
• Molecular weight (via static light scattering, model‑dependent)
• Particle concentration / titre (model‑dependent) 

Measurement Principles

Particle size

• Dynamic Light Scattering (DLS)
• Non‑Invasive Back Scatter (NIBS®)
• Optional Multi‑Angle DLS (MADLS®) on advanced models

Zeta potential

• Electrophoretic Light Scattering (ELS)
• Phase Analysis Light Scattering (M3‑PALS®)
• Constant current mode for improved stability measurements 

Molecular weight

• Static Light Scattering (SLS), model‑dependent

Typical Technical Performance

Particle size range

• Approx. 0.3 nm to 10–15 µm (depending on optical configuration and model) 

Zeta potential range

• Typically > ±500 mV, conductivity‑dependent

Minimum sample volume

• As low as 3–12 µL (sample cell and model dependent) 

Temperature control

• Integrated temperature control (typically 0–90 °C, model dependent)

Sample Compatibility

• Nanoparticles and colloids
• Proteins, antibodies, and polymers
• Emulsions, dispersions, and suspensions
• Aqueous and certain non‑aqueous systems
• High‑salt and low‑concentration samples (model‑dependent) 

Hardware and Design Features

• Compact bench‑top footprint
• Laser‑based optical system with fixed or multi‑angle detection
• Broad range of disposable and reusable cuvettes and capillary cells
• Integrated temperature control and condensation management
• Low‑maintenance, alignment‑free optical 

Software and Data Handling

• Dedicated Zetasizer software (ZS XPLORER / Zetasizer Advance software, model‑dependent)
• Automated method setup and data quality guidance
• Advanced data analysis, reporting, and export functions
• Optional support for 21 CFR Part 11 / regulated environments (model‑dependent)

Camag Automatic HPTLC System

Revolutionizing High-Performance Thin-Layer Chromatography with Full Automation

The Camag Automatic HPTLC System represents a new standard in high-performance thin-layer chromatography (HPTLC), delivering fully automated chromatographic analysis from sample application through development, derivatization and detection. Built on Camag’s decades of innovation and Swiss precision engineering, this system maximizes throughput, reproducibility and analytical confidence for routine quality control, complex sample analysis and high-volume laboratory workflows.

Key Features & Capabilities

• End-to-End Automation – Seamlessly integrates all key HPTLC process steps into one connected platform, eliminating manual handling between application, development and detection modules.
• High Throughput & Efficiency – Processes multiple HPTLC glass plates (20 × 10 cm) and up to 75 sample applications autonomously, enabling efficient overnight or unattended operation.
• Precision Sample Application – Software-controlled application ensures highly accurate band placement and volume delivery, critical for robust qualitative and quantitative results.
• Automated Development Control – Advanced developing chambers actively regulate gas phase and solvent conditions for highly reproducible separations across different analytes.
• Automated Derivatization & Detection – Reagents are applied with precise, automated spraying; integrated heating accelerates visualization of analytes — all controlled via intuitive software.
• Integrated Software (visionCATS) – Comprehensive control and data management software unifies instrument operation, method setup, and result evaluation with ease.

Benefits You Can Count On

• Reliable, Reproducible Results – Automation removes variability from manual processes, delivering consistent analytical quality run after run.
• Enhanced Productivity – Reduce hands-on time and accelerate lab workflows while maintaining the flexibility of HPTLC for diverse sample types.
• Minimal Solvent Waste – Optimized fluid handling and automated procedures help keep operating costs and solvent consumption low.
• Flexible Configuration – Modular design allows stand-alone use or scalable integration into broader laboratory automation infrastructures.