Biotechnology
Purification/chromatography
The ÄKTA Avant 25 is a high-performance liquid chromatography system developed by Cytiva for method and process development in protein purification. It is designed to support a wide range of chromatography techniques including:
- Affinity chromatography
- Ion exchange chromatography
- Size exclusion (gel filtration) chromatography
- Hydrophobic interaction chromatography
Key Features
- Flow rate: 0.001 to 25 mL/min
- Pressure range: Up to 10 MPa (100 bar)
- UV detection: 190–700 nm range, with simultaneous multi-wavelength monitoring
- Built-in fraction collector: Can collect up to 576 fractions with cooling capability
- Modular design: Includes system pumps, sample pumps, mixers, valves, and sensors for pressure, pH, conductivity, and UV
- Automation: Supports automated gradient formation, sample injection, and fraction collection
- Software: Controlled via UNICORN software for method development, data analysis, and system control
ÄKTA pure™ Chromatography System — Flexible, Reliable Protein Purification
The ÄKTA pure™ system from Cytiva is a highly versatile, modular chromatography platform engineered to support a wide range of biomolecule purification workflows. Designed for research environments that demand precision, flexibility, and reproducibility, ÄKTA pure combines robust hardware with intuitive UNICORN™ software to deliver high‑quality results across protein, peptide, and other biomolecule purification tasks.
Modular Design for Custom Workflows
- Configure the system to your exact purification needs with more than 20 hardware options, including advanced UV monitors and multiple pump and detector choices.
- Choose between ÄKTA pure 25 (up to 25 mL/min) or ÄKTA pure 150 (up to 150 mL/min) to match your required flow rate and scale.
Powerful Detection & Monitoring
- Detect biomolecules with triple‑wavelength UV monitoring, or select fixed or dual‑wavelength options depending on your application.
- Integrated pH and conductivity monitoring ensures precise control of gradients and elution conditions.
High Flexibility in Sample & Buffer Handling
- Connect up to 10 chromatography columns with automated switching for seamless method execution.
- Utilize 14 buffer inlets with air sensors for safe, flexible buffer selection during complex workflows.
- Collect fractions using tubes or plates for high‑capacity, customizable sample handling.
Reliable Performance Backed by Decades of Expertise
- Built on over 50 years of protein research and three decades of ÄKTA system development, ÄKTA pure delivers trusted performance and reproducibility in every run.
- Supports a broad range of chromatography techniques, from affinity and ion exchange to size exclusion and hydrophobic interaction chromatography.
Intuitive Software Integration
- UNICORN™ software provides streamlined method creation, real‑time system control, and powerful evaluation tools for data analysis and documentation.
The ÄKTA™ start from Cytiva is a compact, easy-to-use chromatography system designed for laboratory-scale protein purification. Built to simplify purification workflows, it automates manual chromatography procedures and enables reliable, reproducible purification of biomolecules such as proteins and antibodies.
Designed as a stand-alone preparative liquid chromatography system, ÄKTA start features an intuitive interface, a simple flow path, and built-in methods that allow researchers to quickly transition from manual purification to automated operation. Its compact footprint makes it ideal for benchtop use in academic, biotechnology, and pharmaceutical research laboratories.
The system supports a wide range of common chromatography techniques, including affinity chromatography, ion exchange, gel filtration (size exclusion), desalting, and buffer exchange. Predefined quick-start methods and editable templates allow users to run purification protocols immediately or create customized workflows for specific applications.
Operation is straightforward via the integrated touchscreen interface, which provides real-time monitoring of UV signals and run parameters. For enhanced functionality, the instrument can be paired with UNICORN™ start control software for experiment design and data analysis, as well as the optional Frac30 fraction collector for automated sample collection.
With a flow rate range of 0.5–5 mL/min and reliable UV detection at 280 nm, ÄKTA start offers a practical and affordable solution for laboratories seeking efficient and automated purification of biomolecules.
Key features
- Compact benchtop system for laboratory-scale purification
- Automated workflows to replace manual chromatography
- Intuitive touchscreen control with real-time monitoring
- Predefined purification methods and customizable protocols
- Compatible with prepacked columns and optional fraction collection
- Ideal for purification of proteins, antibodies, and tagged biomolecules
Typical applications
- Protein purification
- Antibody purification
- Affinity and ion-exchange chromatography
- Desalting and buffer exchange
- Sample clean-up prior to downstream analysis
Bioreactor fermentation
Stainless steel stirred bioreactor
| Specifications: | |
| Working volume | 50 L (minimal 30 L) |
| Mantel volume | 6 L |
| Min/max operating pressure - vessel | 3 Bar |
| Min/max operating pressure - mantle | 2.6 Bar |
| Max operating temerature - vessel/mantle | 145 ºC |
DO monitoring and pH control available. Fixed stirring speed max 400 rpm.
Reactor for bioprocess production in 300 liter scale
(Biotechnology environment)
Specifications:
- Working volume: 270-280 liter
- Mantle volume: 15 liter
- Equipped with pH-, DO and temperature control.
Incubation
Eppendorf New Brunswick™ S41i CO₂ Incubator Shaker
1. Product Overview
The Eppendorf New Brunswick S41i is a medium-sized, stackable CO₂ incubator shaker designed for mammalian cell culture, suspension cultures, and applications requiring simultaneous shaking and static incubation. It integrates CO₂ control, an orbital shaker, and high-temperature disinfection in a single compact unit.
2. Key Features
Integrated Shaker + CO₂ Incubator System
- Two-in-one system: shaker platform plus perforated shelf for simultaneous static incubation.
- Innova triple-eccentric drive for stable, uniform, low-vibration shaking.
- Fanless, seamless chamber minimizes contamination and simplifies cleaning.
Contamination Control
- 120 °C high‑temperature disinfection system for thorough decontamination.
- Smooth stainless-steel interior with no fan—reduces turbulence and contamination points.
Space‑Saving, Flexible Design
- Stackable (up to 2 units) for increased capacity in limited spaces.
- Fits under a bench or in small lab footprints.
Vessel Flexibility
- Supports tubes, plates, and flasks up to 5 L, e.g., 10×1 L Erlenmeyer flasks.
3. Technical Specifications
General
Capacity 170 L
Temperature Range ambient + 5 °C to 80 °C)
CO₂ Control Range 0.2–20%
Disinfection 120 °C high‑temperature disinfection system Chamber Design Seamless, fanless stainless-steel chamber
Shaking Performance
Shaking Speed Range 25–400 rpm (25–250 rpm when stacked) Orbit Diameter 25 mm (2.5 cm)
Drive System Innova triple-eccentric drive located outside the chamber
Load Capacity Up to 11 kg (24 lb) on shaker platform
Controls & Interface
User Interface Intuitive touchscreen control
Monitoring Real-time and historical condition logging
4. Applications
- Suspension cultures (CHO, HEK293, Vero cells)
- Mammalian inoculum preparation
- Hybridoma cultures
- Microcarrier-based expansion (MSCs, iPSCs)
- Static + shake flask parallel workflows within one instrument
Spray drying
Büchi Mini Spray Dryer B‑290
The Büchi Mini Spray Dryer B‑290 is a laboratory‑scale spray drying system designed for the efficient, gentle, and reproducible conversion of liquid feeds into dry powders. It is one of the most widely adopted spray dryers in research and development laboratories, supporting a broad range of applications in food, pharmaceutical, chemical, and materials science research.
The B‑290 enables spray drying of aqueous solutions, suspensions, and organic solvent‑based systems, producing particles with controlled size and morphology in a single, continuous process. Its short residence time and evaporative cooling effect allow even temperature‑sensitive materials to be processed without significant thermal degradation.
A key feature of the system is its robust glass assembly, which provides full visual access to the spray drying process, facilitating method development, troubleshooting, and teaching. The instrument includes a high‑precision two‑fluid nozzle with integrated cleaning mechanism, ensuring stable atomization and reproducible particle formation across extended runs.
The Mini Spray Dryer B‑290 supports a wide range of spray drying operations, including:
- Spray drying of solutions and suspensions
- Micro‑encapsulation and coating
- Particle size modification and agglomeration
- Spray crystallization
Typical application areas include formulation development, encapsulation of bioactive compounds, flavor and aroma stabilization, functional food ingredients, pharmaceuticals, and advanced materials research.
The system can be combined with dedicated Büchi accessories, such as inert gas loops and dehumidification units, enabling safe processing of organic solvents and improved control of ambient conditions when required.
Homogenization
GEA PandaPLUS 1000 – High Pressure Homogenizer
Overview
The GEA PandaPLUS 1000 is a compact, tabletop high‑pressure laboratory homogenizer designed for continuous operation at up to 1000 bar, ideal for processing nanoparticles, nanoemulsions, nanodispersions, and for efficient cell disruption. It is widely used across food, dairy, cosmetic, chemical, and pharmaceutical applications and delivers results scalable to industrial systems.
Key Performance Data
Max Pressure: 1000 bar
Flow Rate: 20–24 L/h depending on electrical configuration (50/60 Hz)
Minimum Sample Volume: 60 mL
Feeding Hopper Volume: 0.4 L standard; 2 L optional
Dimensions (L × W × H): 810 × 540 × 440 mm
Weight: 105 kg
Viscosity Limit Without Feeding Pump: Up to 1000 cP
Construction & Materials
Compression Block
- High‑grade Super Duplex stainless steel engineered for high stress resistance.
- Solid ceramic pumping piston.
- No lubrication water required (special packing design).
- Suction ball valve (PVB) in ceramic; replaceable seat in hardened stainless steel or optional tungsten carbide.
Homogenizing Valve
- Manual pressure adjustment via hand‑wheel.
- Reversible wear parts in tungsten carbide (ceramic optional).
- Second-stage homogenizing valve included as standard.
- Multiple outlet orientations: front/upwards/downwards.
Power End
- Three‑phase motor, suitable for variable speed drive.
- Camshaft drive system with maintenance‑free grease lubrication.
Casing & Frame
- ABS removable casing for easy cleaning.
- High‑quality stainless steel base frame.
- Adjustable anti‑vibration rubber feet.
Control System
- Touch‑screen control panel.
- Start/stop control and pressure trend visualization.
- Built‑in safety system for overpressure protection.
Product Inlet/Outlet
- Tri‑Clamp™ connections for inline installation.
- No feeding pump required when product viscosity ≤ 1000 cP.
Applications (Note; this equipment is placed in biotech/GMO environment)
Suitable for continuous high‑pressure processing of:
- Nanoparticles, nanoemulsions, nano‑dispersions
- Cell disruption
- Dairy products & fruit juices
- Liquid foods, additives, and ingredients
- Cosmetic & chemical products